京都大学医学部附属病院 循環器内科

発表論文(英文) – 2009年

  1. Nakagawa Y, Nobuyoshi M, Yamaguchi T, Meguro T, Yokoi H, Kimura T, Hosoda S, Kanmatsuse K, Matsumori A, Sasayama S. Efficacy of abciximab for patients undergoing balloon angioplasty: data from Japanese evaluation of c7E3 Fab for elective and primary PCI organization in randomized trial (JEPPORT). Circ J.Jan 2009;73(1):145-151.
  2. Furukawa Y, Ehara N, Taniguchi R, Haruna Y, Ozasa N, Saito N, Doi T, Hoshino K, Tamura T, Shizuta S, Abe M, Toma M, Morimoto T, Teramukai S, Fukushima M, Kita T, Kimura T. Coronary Risk Factor Profile and Prognostic Factors for Young Japanese Patients Undergoing Coronary Revascularization. Circ J. 2009 Aug; 73(8): 1459-65.
  3. Kimura T, Morimoto T, Nakagawa Y, Tamura T, Kadota K, Yasumoto H, Nishikawa H, Hiasa Y, Muramatsu T, Meguro T, Inoue N, Honda H, Hayashi Y, Miyazaki S, Oshima S, Honda T, Shiode N, Namura M, Sone T, Nobuyoshi M, Kita T, Mitsudo K. Antiplatelet Therapy and Stent Thrombosis After Sirolimus-eluting Stent Implantation. Circulation 2009;119(7);987-995.
  4. Nishiyama k, Shizuta S, Doi T, Morimoto T, Kimura T. Sudden cardiac death after PCI and CABG in the bare-metal stent era:Incidence, prevalence, and predictors. Int J Cardiol 209 Feb.6 in press
  5. Nishiyama k; Morimoto T; Shizuta S; Doi T; Kita T; Kimura T. Chronic Obstructive Pulmonary Disease?an Independent Risk Factor for Long-term Cardiac and Cardiovascular Mortality in Patients with Ischemic Heart Disease. Int J Cardiol. 109 Apr 13 in press
  6. Nishiyama K; Horiguchi M; Sakata R; Okabayashi H; Yamanaka K; Ushijima T; Nishiwaki N; Okada Y; Tanaka K; Shimamoto M; Asai T; Aota M; Tahata T; Matsuda K; Nakajima H; Kawasuji M; Komiya T; Furukawa Y; Nakagawa Y; Ehara N; Taniguchi R; Haruna Y; Shizuta S; Doi T; Fukushima M; Kita T; Kimura T. Temporal Pattern of Strokes after On-Pump and Off-Pump Coronary Artery Bypass Graft Surgery. Ann Thorac Surg. 2009 Jun:87(6):1839-44
  7. Abe M; Kimura T; Morimoto T; Furukawa Y; Kita T. Incidence of and Risk Factors for Contrast-Induced Nephropathy After Cardiac Catheterization in Japanese Patients. Circ J 2009; 73(8): 1518 -1522
  8. Hiro T; Kimura T; Morimoto T; Miyauchi K; Nakagawa Y; Yamagishi M; Ozaki Y; Kimura K; Saito S; Yamaguchi T; Daida H; Matsuzaki M; for the JAPAN-ACS Investigators.Effect of Intensive Statin Therapy on Regression of Coronary Atherosclerosis in Patients with Acute Coronary Syndrome: A Multi-center Randomized Trial Evaluated by Volumetric Intravascular Ultrasound using Pitavastatin versus Atorvastatin (JAPAN-ACS Study) J Am Coll Cardiol. 2009 Jul 21;54(4):293-302.
  9. Toyofuku M, Kimura T, Morimoto T, Hayashi Y, Ueda H, Kawai K, Nozaki Y, Hiramatsu S, Miura A , Yokoi Y, Toyoshima S, Nakashima H, Haze K , Tanaka M, Take S,Saito S, Isshiki T, Mitsudo K, on behalf of the j-Cypher Registry Investigators. Three-Year Outcomes After Sirolimus-Eluting Stent Implantation forUnprotected Left Main Coronary Artery Disease: Insights from the j-Cypher Registry. Circulation. 2009 Nov 10;120(19):1866-74. Epub 2009 Oct 26.
  10. Kimura T; Isshiki T; Hayashi Y; Oshima S;Namura M; Nakashima H; Kawai K; Sone T; Tatami R; Meguro T; Nobuyoshi M; Mitsudo K. Incidence and Outcome of Surgical Procedures After Sirolimus-eluting Stent Implantation: A report from the j-Cypher registry. Cardiovasc Interv and Ther. 13 November 2009
  11. Mima A, Toma M, Matsubara T, Shiota F, Iehara N, Abe H, Nagai K, Takahashi T, Matsuura M, Murakami T, Kishi S, Araoka T, Kishi F, Kondo N, Shigeta R, Yoshikawa K, Kimura T, Kita T, Doi T, Fukatsu A. Angio-embolization of renal artery pseudoaneurysm after renal biopsy: a case report. Ren Fail. 2009;31(8):753-5.
  12. Yoshihiro Morino, Takeshi Kimura, Yasuhiko Hayashi, Toshiya Muramatsu, Masahiko Ochiai, Yuichi Noguchi, Kenichi Kato, Yoshisato Shibata, Yoshikazu Hiasa, Osamu Doi, Takehiro Yamashita, Takeshi Morimoto, Mitsuru Abe, Kazuaki Mitsudo. In-hospital Outcomes of Contemporary Percutaneous Coronary Intervention in Patients with Chronic Total Occlusion: Insights from the J-CTO Registry JACC-Cardiovascular Intervention in press.
  13. Shinichi Shirai , Masakiyo Nobuyoshi , Takeshi Morimoto , Kenji Ando , Yoshimitsu Soga , Kyohei Yamaji , Katsuhiro Kondo , Koyu Sakai , Takeshi Arita , Masahiko Goya , Masashi Iwabuchi , Hiroyoshi Yokoi , Hideyuki Nosaka , Kazuaki Mitsudo. Impact of Multiple and Long Sirolimus-Eluting Stent Implantation on Three-Year Clinical Outcomes in the j-Cypher Registry JACC-Cardiovascular Intervention in press.
  14. Natsuhiko Ehara, Takeshi Morimoto, Yutaka Furukawa, Satoshi Shizuta, Ryoji Taniguchi, Yoshihisa Nakagawa, Kozo Hoshino, Naritatsu Saito, Takahiro Doi, Yoshisumi Haruna, Neiko Ozasa, Yukiko Imai, Satoshi Teramukai, Masanori Fukushima, Toru Kita, Takeshi Kimura. Impact of Baseline Glycemic Level on Long-Term Cardiovascular Outcomes after Coronary Revascularization Therapy in Patients with Type 2 Diabetes Mellitus Treated with Hypoglycemic Agents American Journal of Cardiology in press
  15. Ozasa N, Morimoto T, Furukawa Y, Hamazaki H, Kita T, Kimura T:Six-Minute Walk Distance in Japanese Healthy Adults General Medicine 2009 in press
  16. Tada T, Fujita M, Goto T, Tamura T, Ono K, Kita T, Takahashi K, Nagata H, Sakata R, Kimura T:A case with sudden onset of position-dependent hypoxemia caused by reopening of foramen ovale Journal of Cardiology Cases 2009 in press
  17. S. Wood, M. Meeths, CC Chiang, A. Bechensteen, J. Boelens, C. Heilmann, H. Horiuchi, S. Rosthoj, O. Rutynowska, J. Winiarski, J. Stow, M. Nordenskjold, J-I Henter, H-G Ljunggren, Y. Bryceson (2009) NK cell activating receptors selectively recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood in press
  18. T. Oga, K. Chin*, A. Tabuchi, K. Sumi, K. Takahashi, T. Handa, K. Takahashi, R. Taniguchi, H. Kondo, M. Kawato, T. Morimoto, M. Mishima, T. Kita, H. Horiuchi (2009) Effects of obstructive sleep apnea with intermittent hypoxia on platelet aggregability, J. Atherosclersis. Thromosis, in press
  19. R. Shirakawa, S. Fukai, M. Kawato, T. Higashi, H. Kondo, T. Ikeda, E. Nakayama, K. Okawa, O. Nureki, T. Kimura, T. Kita, H. Horiuchi (2009) Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase activating proteins for Ral GTPases. J. Biol. Chem., 284, 21580-21588.
  20. S. Katsuragi, S. Ohga, H. Horiuchi, T. Hara, K. Terano, T. Ikeda(2009) Neonatal onset hemophagocytic lymphohistiocytosis in a premature infant. Pediat. Blood Cancer 53, 244-245
  21. T. Jinnai, H. Horiuchi*, T. Makiyama, J. Tazaki, T. Tada, M. Akao, K. Ono, K. Hoshino, Y. Naruse, K. Takahashi, H. Watanabe, T. Kita, T. Kimura (2009) The Impact of CYP2C19 Polymorphism on the antiplatelet effect of clopidogrel in the real clinical setting. Circ. J, 73, 1498-1503.
  22. K. Hoshino, H. Horiuchi*, T. Tada, J. Tazaki, E. Nishi, M. Kawato, T. Ikeda, H. Yamamoto, M. Akao, Y. Furukawa, S. Shizuta, M. Toma, T. Tamura, N. Saito, T. Doi, N. Ozasa, T. Jinnai, K. Takahashi, H. Watanabe, Y. Yoshikawa, N. Nishimoto, C. Ouchi, T. Morimoto, T. Kita, T. Kimura (2009) Clopidogrel resistance in Japanese patients scheduled for percutaneous coronary intervention. Circ. J 73, 336-342.
  23. Nagao-K, Ono-K, Iwanaga-Y, Tamaki-Y, Kojima-Y, Horie-T, Nishi-H, Kinoshita-M, Kuwabara-Y, Hasegawa-K, Kita-T, Kimura-T. Neural cell adhesion molecule is a cardioprotective factor up-regulated by metabolic stress. Journal of Molecular and Cellular Cardiology. 2009 in press.
  24. Nakashima-Y, Ono-K, Yoshida-Y, Kojima-Y, Kita-T, Tanaka-M, Kimura-T. The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting. Biochem Biophys Res Commun.2009 Dec 18;390(3):821-826.
  25. Horie-T, Ono-K, Nishi-H, Iwanaga-Y, Nagao-K, Kinoshita-M, Kuwabara-Y, Takanabe-R, Hasegawa-K, Kita-T, Kimura-T. MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes. Biochem Biophys Res Commun.2009;389:315-20.
  26. Takaya T, Ono K, Kawamura T, Takanabe R, Kaichi S, Morimoto T, Wada H, Kita T, Shimatsu A, Hasegawa K. MicroRNA-1 and MicroRNA-133 in Spontaneous Myocardial Differentiation of Mouse Embryonic Stem Cells. Circulation J. 2009;73:1492-7.
  27. Kojima Y, Ono K, Inoue K, Takagi Y, Kikuta K-I, Nishimura M, Yoshida Y, Nakashima Y, Matsumae H, Furukawa Y, Mikuni N, Nobuyoshi M, Kimura T, Kita T, Tanaka M. Progranulin Expression in Advanced Human Atherosclerotic Plaque Atherosclerosis. 2009;206:102-108.
  28. Sugimoto M, Arai H, Tamura Y, Murayama T, Khaengkhan P, Nishio T, Ono K, Ariyasu H, Akamizu T, Ueda Y, Kita T, Harada S, Kamei K, Yokode M. Mulberry leaf ameliorates the expression profile of adipocytokines by inhibiting oxidative stress in white adipose tissue in db/db mice. Atherosclerosis. 2009;204:388-94.
  29. Nishi-H, Ono-K, Iwanaga-Y, Horie-T, Nagao-K, Takemura-G, Kinoshita-M, Kuwabara-Y, Takanabe Mori-R, Hasegawa-K, Kita-T, Kimura-T. MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via ARL2 in neonatal rat cardiac myocytes. J Biol Chem. 2009 in press
  30. Ohno M, Hiraoka Y, Matsuoka T, Tomimoto H, Takao K, Miyakawa T, Oshima N, Kiyonari H, Kimura T, Kita T, and *Nishi E. (*Corresponding author) Nardilysin Regulates Axonal Maturation and Myelination in the Central and Peripheral Nervous System Nat. Neurosci. 2009; 12: 1506-1513
  31. Nishio Y, Makiyama T, Itoh H, Sakaguchi T, Ohno S, Gong YZ, Yamamoto S, Ozawa T, Ding WG, Toyoda F, Kawamura M, Akao M, Matsuura H, Kimura T, Kita T, Horie M. D85N, a KCNE1 polymorphism, is a disease-causing gene variant in long QT syndrome. J Am Coll Cardiol. 2009 Aug 25;54(9):812-9.
  32. Ohno S, Toyoda F, Zankov DP, Yoshida H, Makiyama T, Tsuji K, Honda T, Obayashi K, Ueyama H, Shimizu W, Miyamoto Y, Kamakura S, Matsuura H, Kita T, Horie M. Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome. Hum Mutat. 2009 Apr;30(4):557-63.
  33. Masashi Kato, Masaharu Akao, Madoka Matsumoto-Ida, Takeru Makiyama, Moritake Iguchi, Toshihiro Takeda, Shigeomi Shimizu, Toru Kita. The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy : evidence from two-photon imaging. Cardiovasc Res. 2009 Jul 15;83(2):335-44.
  34. Itoh H, Sakaguchi T, Ding WG, Watanabe E, Watanabe I, Nishio Y, Makiyama T, Ohno S, Akao M, Higashi Y, Zenda N, Kubota T, Mori C, Okajima K, Haruna T, Miyamoto A, Kawamura M, Ishida K, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Sugimoto Y, Ashihara T, Hayashi H, Ito M, Imoto K, Matsuura H, Horie M. Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome. Circ Arrhythm Electrophysiol. 2009 Oct;2(5):511-23.
  35. Nakagawa Y, Kuwahara K, Takemura G, Akao M, Kato M, Arai Y, Takano M, Harada M, Murakami M, Nakanishi M, Usami S, Yasuno S, Kinoshita H, Fujiwara M, Ueshima K, Nakao K. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. Circ Res. 2009 Oct 9;105(8):746-54 36. Inuzuka Y, Okuda J, Kawashima T, Kato T, Niizuma S, Tamaki Y, Iwanaga Y, Yoshida Y, Kosugi R, Watanabe-Maeda K, Machida Y, Tsuji S, Aburatani H, Izumi T, Kita T, Shioi T. Suppression of Phosphoinositide 3-kinase Prevents Cardiac Aging in Mice. Circulation 2009; 120:1695-703.
  36. Pretorius L, Du XJ, Woodcock EA, Kiriazis H, Lin RC, Marasco S, Medcalf RL, Ming Z, Head GA, Tan JW, Cemerlang N, Sadoshima J, Shioi T, Izumo S, Lukoshkova EV, Dart AM, Jennings GL, McMullen JR. Reduced Phosphoinositide 3-Kinase (p110{alpha}) Activation Increases the Susceptibility to Atrial Fibrillation. Am J Pathol. 2009; 175: 998-1009.
  37. Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM. Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function. Am J Physiol Heart Circ Physiol. 2009; 296(3): H566-72.
  38. Hirokazu Mitsuoka, Noriaki Kume, Kazutaka Hayashida, Atsuko Inui-Hayashiada, Yo Aramaki, Masako Toyohara, Toshikazu Jinnai, Eiichiro Nishi, Toru Kita Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1). Atherosclerosis vol. 202: 176-182, 2009
  39. Fumihiko Kamezaki, Kazuhito Yamashita, Hiromi Tasaki, Noriaki Kume, Hirokazu Mitsuoka, Toru Kita, Tetsuo Adachi, Yutaka Otsuji Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 correlates with oxidative stress markers in stable coronary artery disease. Int. J. Cardiol. vol. 134: 285-287, 2009
  40. Yasuhiro Nomata, Noriaki Kume, Hiroyuki Sasaki, Yasutomi Katayama, Yoshio Nakata, Tomohiro Okura, Kiyoji Tanaka Weight reduction can decrease circulating soluble lectin-like oxidized LDL receptor-1 (sLOX-1) levels in overweight middle-aged men. Metabolism vol. 59: 1209-1214, 2009
  41. Hirokazu Mitsuoka, Masako Toyohara, Noriaki Kume, Kazutaka Hayashida, Toshikazu Jinnai, Masaru Tanaka, Toru Kita Circulating soluble SR-PSOX/CXCL16 as a biomarker for acute coronary syndrome -comparison with high-sensitivity C-reactive protein. J. Atheroscler. Thromb. vol. 16: 586-593, 2009
  42. Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Yabe D, Takagi K, Akama TO, Kita T, Kimura T, Nakamura T. Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc Natl Acad Sci USA 106 : 19029-34, 2009
  43. Hamasu S, Morimoto T, Kuramoto N, Horiguchi M, Iwami T, Nishiyama C, Takada K, Kubota Y, Seki S, Maeda Y, Sakai Y, Hiraide A. Effects of BLS training on factors associated with attitude toward CPR in college students. Resuscitation, 80: 359-364, 2009
  44. Atsuko Y. Higashi, Tomokatsu Ikawa, Masamichi Muramatsu, Aris N. Economides, Akira Niwa, Tomohiko Okuda, Andrew J. Murphy, Jose Rojas, Toshio Heike, Tatsutoshi Nakahata, Hiroshi Kawamoto, Toru Kita, and Motoko Yanagita Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2 Journal of Immunology 182 (9):5633-40, 2009.
  45. Kentaro Suzuki, Aris Economides, Motoko Yanagita, Daniel Graf, Gen Yamada. New horizons at the caudal embryos: coordinated urogenital/reproductive organ formation by growth factor signaling. Curr Opin Genet Dev. 2009 Sep 16. in press.
  46. Motoko Yanagita BMP modulators regulate the function of BMP during body patterning and disease progression Biofactors 35(2):113-9, 2009.
  47. Yoshida Y, Takahashi K, Okita K, Ichisaka T, and Yamanaka S. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell. 2009 Sep 4;5(3):237-241.
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