京都大学医学部附属病院 循環器内科

発表論文(英文) – 2000年

  1. Sasayama S, Okada M, Matsumori A: Chemokines and cardiovascular diseases. Cardiovasc Res 45: 267-269.
  2. Pristipino C, Beltrame JF, Finocchiaro ML, Hattori R, Fujita M, Mongiardo R, Cianflone D, Sanna T, Sasayama S, Maseri A: Major racial differences in coronary constrictor response between Japanese and Caucasians with recent myocardial infarction. Circulation 101: 1102-1108.
  3. Sasayama S, Beltrame J, Hattori R, Fujita M, Yoshida A, Hashimoto T, Tamaki S, Takahashi M, Kida M, Finocchiaro ML, Maseri A: Racial differences in coronary vasoreactivity between Japanese and Caucasian. In Coronary Artery Spasm, ed. by Yasue H, Axel Springer Japan Publishing, Tokyo, pp. 97-100.
  4. Sasayama S: Inotropic therapy in congestive heart failure. In Cardiovascular Pharmacotherapy: Proceedings of the 9th International Congress on Cardiovascular Pharmacotherapy, ed. by Reyes AJ, Maranhao MFC, Monduzzi Editore, Bologna, 2000, pp. 97-101.
  5. Matsumori A, Hara M, Ono K, Hwang MW, Miyamoto T, Sasayama S: Mast cells cause apoptosis of cardiomyocytes and proliferation of other intramyocardial cells in vitro. In Cardiovascular Pharmacotherapy: Proceedings of the 9th International Congress on Cardiovascular Pharmacotherapy, ed. by Reyes AJ, Maranhao MFC, Monduzzi Editore, Bologna, 2000, pp. 339-345.
  6. Ono K, Matsumori A: Inflammatory heart disease. In Congestive heart failure, Second Edition, edited by Jeffrey D. Hosenpud and Barry H. Grrenberg. Lippincott Williams & Wilkins, Philadelphia, pp. 313-323.
  7. Sato Y, Taniguchi R, Yamada T, Nagai K, Makiyama T, Okada H, Matsumori A, Sasayama S, Takatsu Y: Measurements of serum concentrations of cardiac troponin T in patients with hypereosinophilic syndrome: A sensitive non-invasive marker of cardiac disorder. Intern Med (letter) 39: 350.
  8. Sato Y, Takatsu Y, Yamada T, Kataoka K, Taniguchi R, Mimura R, Sasayama S, Matsumori A: Treatment with interferon of dilated cardiomyopathy and striated myopathy associated with hepatitis C virus infection based on serial measurements of serum concentrations of cardiac troponin T. Jpn Circ J 64: 321-324.
  9. Matsumori A, Ono K, Nishio R, Nose Y, Sasayama S: Amlodipine inhibits the production of cytokine induced by ouabain. Cytokine 12: 294-297.
  10. Matsumori A: 1.3 Cytokines and heart failure:Pathophysiological roles and therapeutic implications. Heart Failure Frontiers in Cardiology ed. by A. Kitabatake, S. Sasayama, G.S. Francis, Springer, pp. 35-45.
  11. Matsumori A: Hepatitis C virus and cardiomyopathy. Herz 25: 249-254.
  12. Kakio T, Matsumori A, Ono K, Ito H, Matsushima K, Sasayama S: Roles and relationship of macrophages and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the ischemic and reperfused rat heart. Lab Invest 80: 1127-1136.
  13. Matsumori A, Yutani C, Ikeda Y, Kawai S, Sasayama S: Hepatitis C virus from the hearts of patients with myocarditis and cardiomyopathy. Lab Invest 80: 1137-1142.
  14. Naruse TK, Matsuzaka Y, Ota M, Katsuyama Y, Matsumori A, Hara M, Nagai S, Morimoto S, Sasayama S, Inoko H: HLA-DQB1*0601 is primarily associated with the susceptibility to cardiac sarcoidosis. Tissue Antigens 56: 52-57.
  15. Nakamura K, Matsumori A, Kusano-Fukushima K, Banba K, Taniyama M, Nakamura Y, Morita H, Matsubara H, Yamanari H, Ohe T: Hepatitis C virus infection in a patient with dermatomyositis and left ventricular dysfunction. Jpn Circ J 64: 617-618.
  16. Matsumori A, Hara M, Nagai R, Izumi T, Ohashi N, Ono K, Sasayama S: Hypertrophic cardiomyopathy as a manifestation of cardiac sarcoidosis. Jpn Circ J 64: 679-683.
  17. Matsumori A: Hepatitis C virus infection in hypertrophic or dilated cardiomyopathy. The Hypertrophied heart ed. by N. Takeda, M. Nagano and N.S. Dhalla, Kluwer Academic Publishers, Boston, pp. 345-353.
  18. Matsumori A, Miyazaki S, Takano H, Ono K, Okada M, Miyamoto T, Nonogi H, Daikoku S, Mitsudo K, Matsunaga Y, Ohnishi T, Daikuhara Y, Sasayama S: Circulating hepatocyte growth factor as a marker of thrombus formation in unstable angina pectoris. Jpn Circ J 64: 805-807.
  19. Matsumori A, Nunokawa Y, Sasayama S: Pimobendan inhibits the activation of transcription factor NF-kB. A mechanism which explains its inhibition of cytokine production and inducible nitric oxide synthase. Life Sci 67: 2513-2519.
  20. Matsumori A, Nunokawa Y, Sasayama S: Nifedipine inhibits of transcription factor NF-kB. Life Sci 67:2655-2661.
  21. Arimura T, Nakamura T, Hiroi S, Satoh M, Takahashi M, Ohbuchi N, Ueda K, Yamaguchi N, Akai J, Matsumori A, Sasayama S, Kimura A: Characterization of human nebulette gene: A polymorphism in an actin-binding morif is associated with non-familial dilated cardiomyopathy. Human Genetics 107: 440-51.
  22. Ohashi N, Matsumori A, Furukawa Y, Ono K, Okada M, Iwasaki A, Miyamoto T, Nakano A, Sasayama S: Role of p38 mitogen-activated protein kinase in neointimal hyperplasia after vascular injury. Arterioscler Thromb Vasc Biol 20: 2521-2526.
  23. Suyama K, Muso E, Yashiro M, Sasayama S: Significant suppressive effect of low-dose temocapril, an ACE inhibitor with biliary excretion, on FGS lesions in hypertensive rats. Nephron 86: 491-498.
  24. Makino T, Ono T, Muso E, Yoshida H, Honda G, Sasayama S: Inhibitory effects of rosmarinic acid on the proliferation of cultured murine mesangial cells. Nephrol Dial Transplant 15: 1140-1145.
  25. Nogaki F, Muso E, Kobayashi I, Kusano H, Shirakawa K, Kamata T, Oyama A, Ono T, Miyawaki S, Yoshida H, Sasayama S: Interleukin 12 induces crescentic glomerular lesions in a high IgA strain of ddY mice, independently of changes in IgA deposition. Nephrol Dial Transplant 15: 1146-1154.
  26. Liu N, Ono T, Suyama K, Nogaki F, Shirakawa K, Maeda M, Kawamura T, Kamata T, Oyama A, Muso E, Sasayama S: Mesangial Factor V expression colocalized with fibrin deposition in IgA nephropathy. Kidney Int 58: 598-606.
  27. Kobayashi I,Muso E, Kusano H, Nogaki F, Miyawaki S, Yoshida H, Sasayama S: The abnormal glycosylation of serum and glomerular IgA in a high IgA strain of ddY mice. Nephrology 5 (suppl): A46.
  28. Yashiro M, Muso E, Itoh T, Oyama A, Hashimoto K, Kawamura T Ono T, Sasayama S: Significantly high regional morbidity of MPO-ANCA related angitis and/or nephritis with respiratory tract involvement after the great earthquake of Kobe in 1995. Am J Kid Dis 35: 889-895.
  29. Kamata T, Nogaki F, Fagarasan S, Sakiyama T, Kobayashi I, Miyawaki S, Ikuta K, Muso E, Yoshida H, Sasayama S, Honjo T: Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA. J Immunol 165: 1387-1394.
  30. Watanabe H, Ono T, Muso E, Matsumori A, Sasayama S: Hepatitis C virus infection manifesting as tubulointerstitial nephritis, cardiomyopathy, and hepatitis. Am J Med (letter) 109: 176-177.
  31. Takeda K, Mitsunami K, Muso E, Kinoshita M, Sasayama S, Nakagawa M: Efficaty of celiprolol in treatment of hypertension in the elderly. Current therapeutic research 61: 49-60.
  32. Wakasugi H, Futami T, Muso E, Ono T, Sasayama S, Inui K: Thrombocytopenia and anemia induced by niceritrol used for amelioration of hyperphosphatemia in a hemodialysis patient. Nephron 86 (letter): 97-98.
  33. Masuda D, Nohara R, Tamaki N, Hosokawa R, Inada H, Hirai T, Chen L, Tadamura E, Kudoh T, Konishi J, Fujita M, Sasayama S: Evaluation of coronary blood flow reserve by 13N-NH3 positron emission computed tomography (PET) with dipyridamole in the treatment of hypertension with the ACE inhibitor (Cilazapril). Ann Nucl Med 14: 353-360.
  34. Tadamura E, Yoshibayashi M, Yonemura T, Kudoh T, Kubo S, Motooka M, Nohara R, Matsumori A, Sasayama S, Matsuda T, Tamaki N, Konishi J: Significant regional heterogeneity of coronary flow reserve in paediatric hypertrophic cardiomyopathy. Eur J Nucl Med 27: 1340-1348.
  35. Hosokawa R, Nohara R, Li L, Tamaki S, Hashimoto T, Tanaka M, Miki S, Sasayama S: Effect of long-term cholesterol-lowing treatment with HMG-CoA reductase inhibitor (Simvastatin) on myocardial perfusion evaluated by thallium-201 single photon emission computed tomography. Jpn Circ J 64: 177-182.
  36. Hirai T, Nohara R, Hosokawa R, Tanaka M, Inada H, Fujibayashi Y, Fujita M, Konishi J, Sasayama S: Evaluation of myocardial infarct size in rat heart by pinhole SPECT. J Nucl Cardiol 7: 107-111.
  37. Horie M, Watanuki M, Ishida H, Tsuji K, Ishida-Takahashi A, Yuzuki Y, Seino Y, Sasayama S: Blockade of cardiac ATP-sensitive K+ channels by cibenzoline targets its pore-forming subunit. J Cardiovasc Pharmacol 35: 434-442.
  38. Kono Y, Horie M, Takano M, Otani H, Xie LH, Akao M, Tsuji K, Sasayama S: The properties of the Kir6.1-6.2 tandem channel co-expressed with SUR2A. Pflugers Arch Eur J Physiol 440: 692-698.
  39. Kubota T, Shimizu W, Kamakura S, Horie M: Hypokalemia-induced Long QT syndrome with an underlying novel missense mutation in S4-S5-linker of KCNQ1. J Cardiovasc Electrophysiol 11: 1048-1054.
  40. Akao M, Sakurai T, Horie M, Otani H, Takano M, Kouchi I, Murakami T, Sasayama S: Angiotensin Ⅱtype 1 receptor blockade abolishes specific KATP channel gene expression in rats with myocardial ischemia. J Mol Cell Cardiol 32: 2239-47.
  41. Haruna T, Horie M, Takano M, Xie LH, Kono Y, Yoshida H, Otani H, Kubota T, Ninomiya T, Akao M, Sasayama S: Alteration of membrane lipid environment by l-palmitoylcarnitine modulates KATP channels in guinea pig ventricular myocytes. Pflugers Arch Eur J Physiol 441: 200-207.
  42. M, Yoshida H, Otani H, Ai T, Nishimoto T, Haruna T, Kono Y, Sasayama S: Long QT syndrome as a cause of cardiac sudden death. In Heart Failure / Frontiers in Cardiology, eds. by Kitabatake A, Sasayama S, Francis GS, Springer, 2000, pp. 105-113.
  43. Yoneda T, Fujita M, Kihara Y, Hasegawa K, Sawamura T, Tanaka T, Inanami M, Nohara R, Sasayama S: Related Articles: Pericardial fluid from patients with ischemic heart disease accelerates the growth of human vascular smooth muscle cells. Jpn Circ J 64: 495-498.
  44. Inagaki K, Kihara Y, Hayashida W, Izumi T, Iwanaga Y, Yoneda T, Takeuchi Y, Suyama K, Muso E, Sasayama S: Anti-Ischemic effect of a novel cardioprotective agent JTV519 is mediated through Specific activation of d-isoform of protein kinase C in rat ventricular myocardium. Circulation 101: 797-804.
  45. Inagaki K, Kihara Y, Izumi T, Sasayama S: The cardioprotective effects of a new 1,4-Benzothiazepine derivative, JTV519, on ischemia/ reperfusion-induced Ca2+ overload in isolated rat hearts. Cardiovascular Drugs and Therapy 14: 489-495.
  46. Iwanaga Y, Kihara Y, Yoneda T, Aoyama T, Sasayama S: Modulation of in vivo cardiac hypertrophy with insulin-like growth factor-1 and angiotensin-converting enzyme inhibitor: relationship between change in myosin isoform and progression of left ventricular dysfunction. J Am Coll Cardiol 36: 635-642.
  47. Kawai M, Kihara Y, Hasegawa K, Matsumori A, Sasayama S: Dilated phase of hypertrophic cardiomyopathy with mid-ventricular obstruction: a case of twenty-year follow-up. Jpn Circ J 64: 623-626.
  48. Araki M, Tanaka M, Hasegawa K, Yokota R, Maeda T, Ishikawa M, Yabuuchi Y, Sasayama S: Nitric oxide inhibition improved myocardial metabolism independent of tissue perfusion during ischemia but not during reperfusion. J Mol Cell Cardiol 32: 375-384.
  49. Wada H, Hasegawa K, Morimoto T, Kakita T, Yanazume T, Sasayama S: A p300 protein as a coactivator of GATA-6 in the transcription of smooth muscle-myosin heavy chain. J Biol Chem 275: 25530-25335.
  50. Araki M, Hasegawa K, Iwai-Kanai E, Fujita M, Sawamura T, Kakita T, Wada H, Morimoto T, Sasayama S: Endothelin-1 as an protective factor against b-adrenergic agonist-induced apoptosis in cardiac myocytes. J Am Coll Cardiol 36: 1411-1418.
  51. Hasegawa K, Iwai-Kanai E, Sasayama S: Neurohormonal regulation of myocardial cell apoptosis in the development of heart failure. J Cell Physiol 186: 11-18.
  52. Morimoto T, Hasegawa K, Kaburagi S, Kakita T, Wada H, Yanazume T, Sasayama S: Calcineurin-GATA4 pathway is involved in b-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes. J Biol Chem in revision.
  53. Aoyama T, Takimoto Y, Pennica D, Inoue R, Shinoda E, Hattori R, Yui Y, Sasayama S: Augmented Expression of Cardiotrophin-1 and Its Receptor Component, gp130, in Both Left and Right Ventricles After Myocardial Infarction in the Rat. J Moll Cell Cardiol 32: 1821-1830.
  54. Kishimoto C, Takamatsu N, Kawamata H, Shinohara H, Ochiai H: Immunoglobulin treatment ameliorates murine myocarditis associated with reduction of neurohumoral activity and improvement of extracellular matrix change. J Am Coll Cardiol 36: 1979-1984.
  55. Shioji K, Kishimoto C, Nakamura H, Toyokuni S, Nakayama Y, Yodoi J, Sasayama S: Upregulation of thioredoxin (TRX) expression in giant cell myocarditis in rats. FEBS Letters 472: 109-113.
  56. Kishimoto C, Takada H, Hiraoka Y, Shinohara H, Kitagawa M: Protection against murine coxsakievirus B3 myocarditis by T cell vaccination. J Moll Cell Cardiol 32: 2269-2277.
  57. Shioji K, Kishimoto C, Nakayama Y, Sasayama S: Strain difference in rats with experimental giant cell myocarditis. Jpn Circ J 64: 283-286.
  58. Nakayama Y, Kishimoto C, Shioji K, Sasayama S: Significance of cytokines in giant cell myocarditis in rats. Pathological comparison to viral myocarditis in mice. Jpn Circ J 64: 977-981.
  59. Kishimoto C, Kawamata H, Sakai S, Shinohara H, Ochiai H: Enhanced production of macrophage inflammatory protein (MIP-2) by in vitro and in vivo infections with encephalomyocarditis virus and modulation of myocarditis with an antibody against MIP-2. J Virol 75: 1294-1300.
  60. Kishimoto C: HLA-antigens and variant angina. Int J Cardiol 73: 283.
  61. Hayashida W, Kihara Y, Yasaka A, Sasayama S: Cardiac calcineurin during transition from hypertrophy to heart failure in rats. Biochem Biophys Res Commun 273: 347-351.
  62. Horiuchi M, Hayashida W, Akishita M, Yamada S, Lehtonen JY, Tamura K, Daviet L, ChenYE, Hamai M, Cui TX, Iwai M, Minokoshi Y: Interferon-gamma induces AT2 receptor expression in fibroblasts by Jak/STAT pathway and interferon regulatory factor-1. Circ Res 86: 233-240.
  63. Fujita M: Heparin and angiogenic therapy. Eur Heart J 21: 270-274.
  64. Miyamoto S, Nagaya N, Satoh T, Kyotani S, Sakamaki F, Fujita M, Nakanishi N, Miyatake K: Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension: comparison with cardiopulmonary exercise testing. Am J Resp Critic Care Med 161: 487-492.
  65. Miwa K, Igawa A, Nakagawa K, Hirai T, Fujita M, Inoue H: Exercise-induced negative U waves in precordial leads as a marker of viable myocardium in patients with recent anterior myocardial infarction. Int J Cardiol 73: 149-156.
  66. Iwakura A, Fujita M, Hasegawa K, Sawamura T, Nohara R, Sasayama S, Komeda M: Pericardial fluid from patients with unstable angina induces vascular endothelial cell apoptosis. J Am Coll Cardiol 35: 1785-1790.
  67. Oya H, Nagaya N, Satoh T, Sakamaki F, Kyotani S, Fujita M, Nakanishi N, Miyatake K: Haemodynamic correlates and prognostic significance of serum uric acid in adult patients with Eisenmenger syndrome. Heart 84: 53-58.
  68. Iwakura A, Tabata Y, Nishimura K, Nakamura T, Shimizu Y, Fujita M, Komeda M: Basic fibroblast growth factor may improve devascularized sternal healing. Ann Thorac Surgery 70: 824-828.
  69. Miyamoto S, Fujita M, Sasayama S: Bidirectional function of coronary collateral channels in humans. Int J Cardiol 75: 249-252.
  70. Iwakura A, Tabata Y, Miyao M, Ozeki M, Tamura N, Ikai A, Nishimura K, Nakamura T, Shimizu Y, Fujita M, Komeda M: Novel method to enhance sternal healing after harvesting bilateral internal thoracic arteries with use of basic fibroblast growth factor. Circulation 102(Suppl III): III307-III311.
  71. Fujita M, Miyamoto S, Sekiguchi H, Eiho S, Sasayama S: Effects of posture on sympathetic nervous modulation in patients with chronic heart failure. The Lancet 356: 1822-1823.
  72. Iwakura A, Fujita M, Ikemoto M, Hasegawa K, Nohara R, Sasayama S, Miyamoto S, Yamazato A, Tambara K, Komeda M: Myocardial ischemia enhances the expression of acidic fibroblast growth factor in human pericardial fluid. Heart Vessels 15:112-116.
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