京都大学医学部附属病院 循環器内科

発表論文(英文) – 1999年

  1. Beltrame JF, Sasayama S, Maseri A: Racial heterogeneity in coronary artery vasomotor reactivity: differences between Japanese and caucasian patients. J Am Coll Cardiol 33: 1442-1452.
  2. Sasayama S, Matsumori A, Kihara Y: New insights into the pathophysiological role for cytokines in heart failure. Cardiovasc Res 42: 557-564.
  3. Sasayama S: Cytokines and Heart Failure. Cardioscopies 72: 264-265.
  4. Sasayama S, Kihara Y, Matsumori A, Hasegawa K: Transition from compensated to decompensated cardiac hypertrophy. Heart Fail Rev 4: 379-388.
  5. Furukawa Y, Matsumori A, Ohashi N, Shioi T, Ono K, Harada A, Matsushima K, Sasayama S: Anti-monocyte chemoattractant protein-1/monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries. Circ Res 84: 306-314.
  6. Gwathmey JK, Kim CS, Hajjar RJ, Khan F, DiSalvo TG, Matsumori A, Bristow MR: Cellular and molecular remodeling in an animal model of dilated cardiomyopathy treated with the b-blocker carteolol. Am J Physiol 276: H1678-H1690.
  7. Ono K, Matsumori A, Furukawa Y, Igata H, Shioi T, Matsushima K, Sasayama S: Prevention of myocardial reperfusion injury in rats by an antibody against monocyte chemotactic and activating factor/monocyte chemoattractant protein-1. Lab Invest 79: 195-203.
  8. Okada M, Matsumori A, Ono K, Miyamoto T, Sasayama S: Hepatocyte growth factor is a major mediator in heparin-induced angiogenesis. Biochem Biophys Res Commun 255: 80-87.
  9. Iwasaki A, Matsumori A, Yamada T, Shioi T, Wang W-Z, Ono K, Nishio R, Okada M, Sasayama S: Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis. J Am Coll Cardiol 33: 1400-1407.
  10. Matsumori A, Ohashi N, Nishio R, Kakio T, Hara M, Furukawa Y, Ono K, Shioi T, Sasayama S: Apical hypertrophic cardiomyopathy and hepatitis C virus infection. Jpn Circ J 63: 433-438.
  11. Hwang MW, Matsumori A, Furukawa Y, Ono K, Okada M, Iwasaki A, Hara M, Sasayama S: FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. Circulation 100: 1322-1329.
  12. Hara M, Matsumori A, Ono K, Kido H, Hwang MW, Miyamoto T, Iwasaki A, Okada M, Nakatani K, Sasayama S: Mast cells cause apoptosis of cardiomyocytes and proliferation of other intramyocardial cells in vitro. Circulation 100: 1443-1449.
  13. Nishio R, Matsumori A, Shioi T, Ishida H, Sasayama S: Treatment of experimental viral myocarditis with interleukin-10. Circulation 100: 1102-1108.
  14. Nakamura T, Ruiz-Lozano P, Lindner V, Yabe D, Taniwaki M, Furukawa Y, Kobuke K, Tashiro K, Lu Z, Andon NL, Schaub R, Matsumori A, Sasayama S, Chien KR, Honjo T: DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon injured arteries. J Biol Chem 274: 22476-22483.
  15. Ono K, Matsumori A, Shioi T, Furukawa Y, Sasayama S: Contribution of endothelin-1 to myocardial injury in a murine model of myocarditis. Acute effects of bosentan, an endothelin receptor antagonist. Circulation 100: 1823-1829.
  16. Yamada T, Matsumori A, Wang WZ, Ohashi N, Shiota K, Sasayama S: Apoptosis in congestive heart failure induced by viral myocarditis in mice. Heart and Vessels 14: 29-37.
  17. Sato Y, Takatsu Y, Kataoka K, Yamada T, Taniguchi R, Sasayama S, Matsumori A: Serial circulating concentrations of C-reactive protein and cytokines in patients with acute left heart decompensation. Clin Cardiol 22: 811-813.
  18. Furukawa Y, Matsumori A, Hwang MW, Hirozane T, Ono K, Shioi T, Sasayama S: Cytokine gene expression during the development of graft coronary artery disease in mice. Jpn Circ J 63: 775-782.
  19. Matsumori A, Igata H, Ono K, Iwasaki A, Miyamoto T, Nishio R, Sasayama S: High doses of digitalis increase the myocardial production of proinflammatory cytokines and worsen myocardial injury in viral myocarditis: A possible mechanism of digitalis toxicity. Jpn Circ J 63: 934-940.
  20. Takashige N, Naruse TK, Matsumori A, Hara M, Nagai S, Morimoto S, Hiramitsu S, Sasayama S, Inoko H: Genetic polymorphisms at the tumour necrosis factor loci (TNFA and TNFB)in cardiac sarcoidosis. Tissue Antigens 54: 191-193.
  21. Ono K, Matsumori A: Inflammatory heart disease. In Congestive heart failure, Second Edition, edited by Jeffrey D. Hosenpud and Barry H. Grenberg. Lippincott Williams & Wilkins, Philadelphia. pp. 313-323.
  22. Kim CS, Matsumori A, Goldberg L, Doye AA, McCoy Q, Gwathmey JK: Effects of ranidipine, a calcium channel antagonist, in an avian model of heart failure. Cardiobascular Drugs and Therapy 13: 455-463.
  23. Imasawa T, Nagasawa R, Utsunomiya Y, Kawamura T, Zhong Y, Makita N, Muso E, Miyawaki S, Maruyama N, Hosoya T, Sakai O, Ohno T: Bone marrow transplantation attenuates murine IgA nephropathy: Role of a stem cell disorder. Kidney Int. 56: 1809-1817.
  24. Muso E, Mune M, Fujii Y, Imai E, Ueda N, Hatta K, Imada A, Miki S, Kuwahara T, Takamitsu Y, Takemura T, Tsubakihara Y, for the Kansai -FGS-Apheresis Treatment (K-FLAT)Study Group: Low density lipoprotein apheresis therapy for steroid-resistant nephrotic syndrome. Kidney Int. 71 (suppl.)S122-S125.
  25. Kawamura T, Muso E, Kamata T, Suyama K, Oyama A, Ono T, Yoshida H, Miyawaki S and Sasayama S: Ultrastructural localization of dominantly increased fibronectin in markedly thickend glomerular basement membrane in selectively mated murine high IgA strain (HIGA mice) Nephron 83: 146-153.
  26. Nogaki F, Kobayashi I, Kusano H, Shirakawa K, Kamata T, Ono T, Muso E, Miyawaki S, Yoshida H, Sasayama S: Relationship between the immunological background and the induction of inflammatory renal lesions by IL-12 in a high IgA strain of ddY mice. Nephrology (suppl.)5: A6-A7.
  27. Makino T, Ono T, Muso E, Honda G and Sasayama S: Suppresive effects of Perilla frutescens on spontaneous IgA nephropathy in ddY mice. Nephron 83: 40-46.
  28. Sakurai M, Muso E, Matsushima H, Ono T, Sasayama S: Rapid normalization of interleukin-8 production after low-density lipoprotein apheresis in steroid-resistant nephrotic syndrome. Kidney Int. 71 (suppl.)S210-S212.
  29. Nogaki F. Muso E,Yashiro M, Kasuno K, Kamata T, Ono T, Sasayama S: Direct Inhibitory Effects of Simvastatin on Matrix accumulation in cultured murine mesangial cells. Kidney Int. 71 (suppl.)S198-S201.
  30. Makino T, Ono T, Ito M, Muso E, Honda G: Effect of Perilla frutescens Extract on nitric oxide production by cultured murine mesangial cells. Biol. Pharm Bull 22(5)476-480.
  31. Machiguchi T, Yoshida H, Yonemoto S, Minakata T. Nomura K. Muso E, Tamura T, Sasayama S: Does circulating erythropoietin reflect progression of IgA npheorpathy? Comparison with urinary N-acetyl-b-D-glucosaminidase. Nephrol. Dial. Transplant. 14(3)635-640.
  32. Kamata T, Muso E, Yashiro M, Kawamura T, Oyama A, Matsushima H, Takeuchi E, Yoshida H and Sasayama S: Up-regulation glomerular extracellurar matrix and transforming growth factor-β expression in RF/J mice. Kidney Int 55: 864-876.
  33. Yashiro M, Muso E, Itoh T, Oyama A, Ono T, Sasayama S: Significantly high incidence and high morbidity of acute renal failure with respiratory tract involvement of p-ANCA-related angitis revealed in Kobe city and the environs after the Kobe earthquake in 1995. Clinical Nephrology (Letter) 51(3)190-191.
  34. Cunningham MA, Ono T, Hewitson TD, Tipping PG, Becker GJ, Hordsworth SR: Tissue factor pathway inhibitor expression in human crescentic glomerulonephritis. Kidney Int. 55: 1311-1318.
  35. Li L, Nohara R, Makita S, Hosokawa R, Hata T, Okuda K, Hamazaki H, Fujita M, Sasayama S: Effect of long-term exercise training on regional myocardial perfusion changes in patients with coronary artery disease. Jpn Circ J 63: 73-78.
  36. Suzuki K, Hasegawa K, Nohara R, Matsumori A, Sasayama S: A patient with hypertrophic cardiomyopathy accompanied by right ventricular dilation of unknown cause. Jpn Circ J 63: 137-140.
  37. Masuda D, Nohara R, Inada H, Hirai T, Chen L, Kanda H, Inubushi M, Tadamura E, Fujita M, Sasayama S: Improvement of regional myocardial and coronary blood flow reserve in a patient treated with enhanced external counterpulsation. – Evaluation by nitrogen-13 ammonia PET -. Jpn Circ J 63: 407-411.
  38. Ishihara S, Nohara R, Makita S, Imai M, Kubo S, Hashimoto T: Immune function and psychological factores in patients with coronary heart disease (I) Jpn Circ J 63: 704-709.
  39. Nohara R, Hosokawa R, Hirai T, Okuda K, Ogino M, Fujibayashi Y, Fujita M, Sasayama S: Basic kinetic of 15-(p-iodophenyl)-3-R, -methylpentadecanoic acid (BMIPP)in canine myocardium. Int J Cardiac Imaging 15: 11-20.
  40. Hosokawa R, Nohara R, Fujibayashi Y, Okuda K, Ogino M, Hirai T, Fujita M, Tamaki N, Konishi J, Sasayama S: Myocardial metabolism of iodine-123-BMIPP in a canine model with ischemia: Implications of perfusion-metabolism mismatch on SPECT images in patients with ischemic heart disease. J Nucl Med 40: 471-478.
  41. Shimomura M, Hamazaki H, Kawahatsu K, Nohara R: Clinical study of a swimming program in the pool and sea for patients with ischemic heart disease. In Adapted Physical Activity, Ed. by Nakata H, Shonan Shuppansha, Fujisawa-Japan, 133-138.
  42. Obayashi K, Horie M, Washizuka T, Sasayama S: On the mechanism of genistein-induced activation of protein kinase A-dependent Cl- conductance in cardiac myocytes. Pflugers Archiv 438: 269-277.
  43. Yoshida H, Horie M, Otani H, Takano M, Tsuji K, Fukunami M, Sasayama S: A novel missense mutation in the pore region of HERG in a long QT syndrome patient causes a severe dominant negative effect on HERG function. J Cardiovas Electrophysiol 10: 1262-1270.
  44. Xie LH, Horie M, Takano M: Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism. Proceedings National Academy of USA 96: 15292-15297.
  45. Takagi S, Kihara Y, Toyoda F, Morita T, Sasayama S, Mitsuiye T: Cold acclimation of guinea-pig depressed contraction of cardiac papillary muscle. Am J Physiol 276: R923-R928.
  46. Kaburagi S, Hasegawa K, Morimoto T, Araki M, Sawamura T, Masaki T, Sasayama S: The role of endothelin-converting enzyme-1 in the development of α1-adrenergic- stimulated hypertrophy in cultured neonatal rat cerdiac myocytes. Circulation 99: 292-298.
  47. Inada T, Fujiwara H, Hasegawa K, Araki M, Yamauchi-Kohno R, Yabana H, Fujiwara T, Tanaka M, Sasayama S: Upregulated expression of cardiac endothelin-1 participates in myocardial cell grwoth in Bio 14.6 Syrian cardiomyopathic hamster. J Am Coll Cardiol 33: 565-571.
  48. Morimoto T, Hasegawa K, Kaburagi S, Kakita T, Masutani H, Kitsis RN, Matsumori A, Sasayama S: GATA-5 is involved in leukemia inhibitory factor-responsive transcription of the b-myosin heavy chain gene in cardiac myocytes. J Biol Chem 274: 12811-12818.
  49. Iwai-Kanai E, Hasegawa K, Araki M, Kakita T, Morimoto T, Sasayama S: a- and b-Adrenergic pathways differentially regulate cell type-specific apoptosis in rat cardiac myocytes. Circulation 100: 305-311
  50. Kakita T, Hasegawa K, Morimoto T, Kaburagi S, Wada H, Sasayama S: p300 protein as a coactivator of GATA-5 in the transcription of cardiac-restricted atrial natriuretic factor gene. J Biol Chem 274: 34096-34102.
  51. Shinoda E, Yui Y, Hattori R, Tanaka M, Inoue R, Aoyama T, Takimoto Y, Mitsui Y, Miyahara K, Shizuta Y, Sasayama S: Tissue factor inhibitor-2 is a novel mitogen for vascular smooth muscle cells. J Biol Chem 274: 5379-5384.
  52. Kishimoto C, Takada H, Hiraoka Y: Intravenous IgG. Supertherapy for myocarditis and acute dilated cardiomyopathy. Circulation 99: 975-976.
  53. Kishimoto C, Lee JD, Shimizu H, Ueda T, Maruya E, Saji H: HLA antigens in patients with variant angina in Japan. Int J Cardiol 70: 249-252.
  54. Kishimoto C, Kawamata H, Sakai S, Shinohara H, Ochiai H: Role of MIP-2 in coxsackievirus B3 myocarditis. J Mol Cell Cardiol 31: 2210-2218.
  55. Horiuchi M, Hayashida W, Akishita M, Daviet L, Lehtonen JYA, Dzau VJ: Stimulation of different subtypes of angiotensin II receptors, AT1 and AT2 receptors, regulates STAT activation by negative crosstalk. Circ Res 84: 876-882.
  56. Tadamura E, Kudoh T, Motooka M, Inubushi M, Shirakawa S, Hattori N, Okada T, Matsuda T, Koshiji T, Nishimura K, Matsuda K, Konishi J: Assessment of Regional and Global Left Ventricular Function by Reinjection Tl-201 and Rest Tc-99m Sestamibi Ecg-Gated Spect: Comparison with Three Dimensional Magnetic Resonance Imaging. J Am Coll Cardiol 33: 991-997.
  57. Motooka M, Matsuda T, Kida M, Inoue H, Hayashi K, Takahashi T, Sasayama S: Single Breath-Hold Left Ventricular Volume Measurement by 0.3-Sec Turbo Fast Low-Angle Shot MR Imaging. Am J Roentgenol 172: 1645-1649.
  58. Tadamura E, Kudoh T, Motooka M, Inubushi M, Okada T, Kubo S, Hattori N, Matsuda T, Koshiji T, Nishimura K, Komeda M, Konishi J: Use of technetium-99m sestamibi ECG-gated single-photon emmision tomography for evaluation of left ventricular function following coronay artery bypass graft: comparison with three-dimensional magnetic resonance imaging. Eur J Nucl Med 26: 705-712.
  59. Suga M, Matsuda T, Komori M, Minato K, Takahashi T: Keyhole method for high speed human cardiac cine MRI. J Magn Reson Im 10: 778-783.
  60. Fujita M, Nakae I, Kihara Y, Hasegawa K, Nohara R, Ueda K, Tamaki S, Otsuka K, Sasayama S: Determinants of collateral development in patients with acute myocardial infarction. Clin Cardiol 22:595-599.
  61. Ikemoto M, Hasegawa K, Kihara Y, Iwakura A, Komeda M, Yamazato A, Fujita M: Development of an enzyme-linked immunosorbent assay for acidic fibroblast growth factor and its clinical application. Clin Chim Acta 283: 171-182.
  62. Fujita M, Kihara Y, Hasegawa K, Nohara R, Sasayama S: Heparin potentiates collateral growth but not growth of intramyocardial endarteries in dogs with repeated coronary occlusion. Int J Cardiol 70: 165-170.
  63. Miwa K, Fujita M, Kameyama T, Nakagawa K, Hirai T, Inoue H: Absence of myocardial ischemia during sudden controlled occlusion of coronary arteries in patients with well-developed collateral vessels. Coronary Artery Dis 10: 459-463.
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