京都大学医学部附属病院 循環器内科

学会発表(国際学会)-2016年

KEYSTONE SYMPOSIA, Noncoding RNAs in Health and Disease February 21-24, Santa Fe, New Mexico, USA

  1. Yasuhide Kuwabara, Takahiro Horie, Shin Watanabe, Osamu Baba, Takeshi Kimura, Koh Ono. Long Intergenic Noncoding RNA and Myogenin Circuitry Promotes Myoblast Differentiation.

KEYSTONE SYMPOSIA, Heart failure: Genetics, Genomics and Epigenetics (Z1) April 3-7, Snowbird, Utah, USA

  1. Yasuaki Nakagawa, Toshio Nishikimi, Koichiro Kuwahara, Kazuwa Nakao and Takeshi Kimura. MiR30-GALNTs axis-mediated O-glycosylation plays an important role in the increased secretion of unprocessed pro-brain natriuretic peptide by failing heart.
  2. Masataka Nishiga, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tetsushi Nakao, Tomohiro Nishino, Daihiko Hakuno, Yasuhiro Nakashima, Koji Hasegawa, Toru Kita, Takeshi Kimura, Koh Ono. MicroRNA-33 promotes cardiac fibrosis by maintaining cellular lipid homeostasis.

KEYSTONE SYMPOSIA, Cardiac Development, Regeneration and Repair (Z2) April 3-7, Snowbird, Utah, USA

  1. Yuta Yamamoto. Modeling the long-QT syndrome associated with a calmodulin mutation using human induced pluripotent stem cells.

American College of Cardiology(ACC)2016:65th Annual Scientific Session & Expo April 2-4,Chicago,USA

  1. Tetsuma Kawaji, Hiroki Shiomi, Takeshi Morimoto, Charles A. Taylor, Takeshi Kimura. Real-world Feasibility of Noninvasive Fractional Flow Reserve Derived from Computed Tomography (Real-FFRCT) Study.
  2. Tetsuma Kawaji, Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Kazushige Kadota, Kenji Ando, Tetsu Mizoguchi, Mitsuru Abe, Mamoru Takahashi, Takeshi Kimura, on behalf of CREDO-Kyoto AMI investigators. Long-term Clinical Outcomes in Patients with ST-segment Elevation Acute Myocardial Infarction Complicated by Cardiogenic Shock.
  3. Hidenori Yaku, Hiroki Shiomi, Takeshi Morimoto, Yugo Yamashita, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Mitsuru Abe, Shinji Miki, Satoshi Shizuta, Koh Ono, Takeshi Kimura on behalf of the CREDO-Kyoto AMI registry investigators.Comparison of Short-and Long-term Mortalities between ST-segment Elevation and Non-ST-segment Elevation Acute Myocardial Infarction.
  4. Yugo Yamashita, Hiroki Shiomi, Takeshi Morimoto, Hidenori Yaku, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Mitsuru Abe, Satoshi Shizuta, Koh Ono, Takeshi Kimura. Long-term Cardiac And Non-cardiac Mortality In ST-elevation Acute Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention: Insight From The CREDO-Kyoto AMI Registry.

TCTAP2016 April 26-29, Seoul, Korea

  1. Takeshi Kimura. Very Long-Term Follow-up (>10 Years) After PCI and CABG.
  2. Junichi Tazaki. Successful revascularization of isolated SMA dissection.

Heart Failure 2016 May 21-24, Florence, Italy

  1. Kuwahara K, Nakagawa Y, Nishikimi T, Kangawa K, Minamino N, Nakao K, Kimura T. MiR30-GALNT1/2 axis-mediated glycosylation at threonine 48 and 71 plays an essential role in the increased secretion of unprocessed pro-brain natriuretic peptide by failing hearts.

American Society of Sports Medicine 63th annual meeting May 31-June 4, 2016, Boston, MA, US

  1. Sato S, Kato T, Otsuki S, Tanaka S, Koshiyama H, Nohara R. Effects of the High Intensity Interval Training on Myocardial Mitochondria Function in Patients with Type 2 Diabetes.

3rd Munich Conference on Cardiac Development June 1-3, Munich, Germany

  1. Yoshida Y. A new cell purification method for pluripotent stem cell-based regeneration.

International Society of Stem Cell Research (ISSCR) Annual meeting 2016 June 22-25, San Francisco, USA

  1. Okubo C, Funakoshi S, Miki K, Takaki T, Hatani T, Nishikawa M, Takei I, Narita M, Inagaki A, Yamanaka S, Yoshida Y. Analysis of Development of Left and Right Ventricular Cardiomyocytes using hiPSCs.

AHA BCVS2016 July 18-21, Phoenix, Arizona, USA

  1. Yasuaki Nakagawa, Toshio Nishikimi, Koichiro Kuwahara, Hideyuki Kinoshita, Chinatsu Yamada, Hideaki Inazumi, Kazuwa Nakao, Takeshi Kimura. Unprocessed proBNP secretion is regulated by MiR30-GALNTs axis dependent O-glycosylation in the pathological myocardium.
  2. Masataka Nishiga, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tetsushi Nakao, Tomohiro Nishino, Daihiko Hakuno, Yasuhiro Nakashima, Noriko Nakazeki, Yuya Ide, Satoshi Koyama, Koji Hasegawa, Toru Kita, Takeshi Kimura, Koh Ono. MicroRNA-33 promotes cardiac fibrosis by maintaining cellular lipid homeostasis.

ESC Congress 2016 August 27-31, Roma, Italy

  1. Takeshi Kimura. Future direction for research in complex PCI.
  2. Takeshi Kimura. ABSORB Japan.
  3. Takeshi Kimura. Imaging for bioresorbable scaffolds – An Asian perspective.
  4. Shizuta Satoshi. A Large-Scale Multi-Center Registry of Patients Undergoing Radiofrequency Catheter Ablation for Atrial Fibrillation: Kansai Plus Atrial Fibrillation Study.
  5. KatoT, Minamino-Muta E, Shioi T, Kimura T. Chronic administration of dehydroepiandrosterone sulfate does not improve survival in rats with hypertensive heart failure.
  6. Toyota T, Morimoto T, Shiomi H, Ando K, Ono K, Shizuta S, Kato T, Saito N, Furukawa Y, Nakagawa Y, Horie M, Kimura T. Ad-hoc versus non-ad-hoc percutaneous coronary intervention strategies in patients with stable coronary artery disease.
  7. Taniguchi T, Morimoto T, Shiomi H, Ando K, Kanamori N, Murata K, Naritatsu S, Sakata R, Kimura T. The long-term clinical outcome of patients with low gradient severe aortic stenosis.
  8. Taniguchi T, Shiomi H, Morimoto T, Furukawa Y, Nakagawa Y, Horie M, Kimura T. Incidence of Heart Failure Hospitalization in Patients With ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention.
  9. Minamino-Muta E, Kato T, Taniguchi T, Morimoto T, Sasaki K, Funasako M, Morishima M, Nakane E, Miyamoto S, Izumi T, Haruna T, Ueyama K, Inoko M, Sakata R, Kimura T, on behalf of CURRENT AS Registry investigators. Impact of the left ventricular mass index on the outcomes of conservatively managed severe aortic stenosis: A report from the CURRENT AS registry.
  10. Harita T. l-cis diltiazem rescues impaired calcium channel inactivation in a patient-specific stem cell model of long-QT syndrome with a CACNA1C mutation.

International conference of obesity and metabolic syndrome (ICOMES) September 3, Seoul, Korea

  1. Ono K. MicroRNAs as a New Mechanism Regulating Obesity and Its Complications.

International Liver Cancer Association 2016 September 9-11, Vancouber

  1. Kasai Y, Hatano E, Nishi E, Toriguchi K, Yoh T, Nishio T, Okuno M, Seo S, Taura K, Yasuchika K, Okajima H, Kaido T, Uemoto S. Nardilysin, a novel biomarker for hepatocellular carcinoma, enhances diethylnitrosamine-induced mice carcinogenesis and cancer cell proliferation via activation of STAT3 signaling pathway.

Hypertension Seoul 2016, The 26th Scientific meeting of the International Society of Hypertension September 24-29, Seoul, Korea

  1. Toshio Nishikimi, Yasuaki Nakagawa, Koichiro Kuwahara, Hideyuki Kinoshita, Chinatsu Yamada, Takeshi Kimura, Kazuwa Nakao. Endogenous plasma NT-BNP is glycosylated and undetectable with the current NT-BNP assay system.
  2. Koichiro Kuwahara, Yasuaki Nakagawa, Toshio Nishikimi, Hideyuki Kinoshita, Hiroyuki Okamoto, Takao Kato, Kenji Kangawa, Naoto Minamino, Kazuwa Nakao, Takeshi Kimura. MiR30-GALNT1/2 axis-mediatede glycosylation regulates the increase in inactive human pro-BNP secretion from failing heart.

ENCORE SEOUL 2016 October 5-7, Seoul, Korea

  1. Takeshi Kimura. BRS, is it appropiate or wrong choice for patients undergoing.
  2. Takeshi Kimura. Bioresorbable Vascular Scaffold: Observations from ABSORB Japan.

APHRS 2016 October 12-15, Seoul, Korea

  1. Shizuta Satoshi. ATP Guide PV Isolation in the AF Ablation: UNmasking Dormant Electrical Reconduction by Adenosine TriPhosphate (UNDER-ATP) Trial.
  2. Shizuta Satoshi. Advantages of Cryoballoon Technique Over Traditional Radiofrequency Devices in the Catheter Ablation for Paroxysmal Arial Fibrillation.
  3. Yoshizawa Takashi. Left Atrial Appendage Flow Velocity and Spontaneous Echo Contrast in Transesophageal Echocardiography are Predictors of Long-Term Success After Catheter Ablation for Non-Paroxysmal Atrial Fibrillation.
  4. Yimin Wuriyanghai. Generation of LMNA knockout human induced pluripotent stem cell lines using the CRISPR/Cas9 nickase system.

TCT2016 October 29-November 2, Washinton

  1. Takeshi Kimura. ABSORB Japan Clinical Outcomes at 2 Years.
  2. Shiomi H, Kyoto University Graduate School of Medicine. Randomized Evaluation of Routine Follow-up Coronary Angiography after Percutaneous Coronary Intervention Trial (ReACT) .
  3. Taniguchi T, Morimoto T, Shiomi H, Ando K, Saito N, Kitai T, Izumi C, Sakata R, Kimura T. Effect of Left Ventricular Ejection Fraction on Long-term Clinical Outcomes in Patients with Severe Aortic Stenosis.

AHA Scientific Session 2016 November 12-16, New Orleans, Louisiana, USA

  1. Nakagawa Y, Nishikimi T, Kuwahara K, Kinoshita H, Inazumi H, Moriuchi K, Kato T, Minamino N, Nakao K, Kimura T. Secretion of proBNP is regulated by MiR30-GALNTs axis dependent O-linked glycosylation in the pathological myocardium.
  2. Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E. Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.  
  3. Yoshida Y. IPS-Cell-Derived Cardiomyocyte Disease Modeling. (Frontiers in Science)
  4. Nakao T, Horie T, Baba O, Nishiga M, Nishino T, Nishi H, Izuhara M, Usami S, Nakaseki N, Koyama S, Ide Y, Kimura T, Ono K. Genetic Ablation of miR-33 Attenuates Inflammation and Reduces Abdominal Aortic Aneurysm Formation.
  5. Nishiga M, Horie T, Kuwabara Y, Baba O, Nakao T, Nishino T, Hakuno D, Nakashima Y, Nagao K, Hasegawa K, Kita T, Kimura T, Ono K. MicroRNA-33 Maintains Cellular Cholesterol Content in Fibroblasts and Fibrotic Response in Heart.
  6. Yamamoto Y. Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome with a CALM2 Mutation.
  7. Hatani T, Funakoshi S, Thomas J Deerinck, Eric A Bushong, Kimura T, Yamanaka S, Mark H Ellisman, Hoshijima M, Yoshida Y.T-tubules and Dyad Formation in Engrafted iPSC-Derived Cardiomyocytes With Stable APEX2 Expression.

Meet the Expert November14, New Orleans, Louisiana

  1. Nishiga M, Ono K. MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol.
  2. Yamamoto Y. Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome with a CALM2.

58th American Society of Hematology (ASH) Annual Meeting and Exposition December 3-6, San Diego, USA

  1. Kazuhisa Chonabayashi, Masahiro Kawahara, Akira Watanabe, Masahiro Nakamura, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida. iPS technology revealed the genetic and functional diversity present in a secondary AML patient.
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